Parkinson’s disease is the second most common degenerative neurological disorder. The incidence of Parkinson’s disease, let’s call it PD for short, is increasing rapidly with the elderly population. The root cause of PD is the death of nerve cells that produce a chemical called dopamine. Damage to these dopamine-producing cells occurs in the part of the brain commonly known as the basal ganglia and specifically the substantia nigra.
This part of the brain is known to affect the basal ganglia, movement and disease or injury to the basal ganglia, which is known as a movement disorder that includes Parkinson’s disease. Parkinson’s disease is characterized by slow movements known as bradykinesia (brady = slow, kinesis = movement), tremors, and other signs of abnormal muscle function. One of the more annoying symptoms that can occur in patients with PD is that the gut freezes.
Voluntary movement occurs in two basic steps. To move we intend to move to one part of the brain. Thus the movement of one part of the brain is planned and the actual movement commands that activate the muscles take place in different parts of the brain. So we plan a movement and that plan is carried out by another circuit in the brain which then executes that plan.
In many patients with Parkinson’s disease, planned execution such as walking delays or fails. This is called Keep cool And it can drastically reduce the quality of life in a Parkinson’s patient. Although we call this symptom cold from the gait, it can actually occur with any voluntary movement, such as reaching for a glass, brushing your hair, or getting bored while sitting. It often causes the Parkinson’s patient to be unable to start movement or to get stuck between planned actions. It should not be difficult for you to imagine how the cold drastically reduces the functional capacity of the patient and interferes with his daily activities.
Not surprisingly, cold is also associated with freezes and injuries in PD patients.
Medical treatment of PD includes drugs that replace dopamine that are lost with the degeneration of the substantia nigra. As a general rule, dopamine replacement therapy is quite effective for patients suffering from PD with two notable exceptions.
They are usually freezing type symptoms and not particularly effective for
They usually loosen their effectiveness over time
A number of research groups believe they have identified a specific part of the brain that causes symptoms of defective cooling in Parkinson’s patients. It is known as the pedunculopontine nucleus (PPN for short) in the reins of the brain. This has led to many tests of the electrical stimulation of the PPN using surgically implanted deep brain electrodes. There are a growing number of reports suggesting that electrical stimulation of PPN can bring promising results for patients with advanced stage Parkinson’s disease. This technique appears to activate the PPN and reduce gait-freezing in patients with Parkinson’s disease. While this is a promising surgical procedure, however, brain surgery and all the risks associated with it are required.
If only the brain had a way to stimulate the PPN in a non-invasive way.
Some recent research suggests that non-surgical PPN stimulation is now possible. More encouraging, therefore, is the possibility of stimulating the PNN and reducing the cooling through the use of musical tones played by special bone management headphones. Let’s see how this works.
Research has shown that inner ear structures called ear tolls can be stimulated by tones of very specific frequencies. These inner ear structures have direct connections with the PPN that we have discussed are important brain structures related to cooling symptoms in Parkinson’s disease. Stimulation of ol toliths by tone played by special bone-operated headphones can activate the PPN and have the potential to reduce gait-freezing in patients with Parkinson’s disease. Other research suggests that neurological rehabilitation and Qing in patients with ory disease or visual signals may improve cooling symptoms in PD patients. Thus, P.P.N. The use of known sound frequencies to stimulate is likely to improve the cooling of the gait by combining rehab with ory dietary quenching which cools the gait in PD.
This is very encouraging news for patients suffering from gate freezing associated with Parkinson’s disease.